Related Experiment Video
Updated: Jun 14, 2026

Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure
Published on: August 25, 2017
Application of a theoretical model to evaluate COPD disease management
Karin M M Lemmens1, Anna P Nieboer, Maureen P M H Rutten-Van Mölken
1Erasmus University Rotterdam, Institute of Health Policy and Management, P,O, Box 1738, 3000 DR Rotterdam, the Netherlands. lemmens@bmg.eur.nl
A theory-driven disease management program for chronic obstructive pulmonary disease (COPD) improved patient outcomes like reduced dyspnea and enhanced experiences. This study highlights the value of theoretical frameworks in evaluating complex health interventions.
Area of Science:
- Pulmonary Medicine
- Health Services Research
- Evidence-Based Practice
Background:
- Disease management programs often lack theoretical underpinnings.
- A novel evaluation model links disease management interventions to outcomes.
- This study evaluates a chronic obstructive pulmonary disease (COPD) management program in primary care.
Purpose of the Study:
- To methodically evaluate the impact of a COPD disease management program.
- To assess effects on process, intermediate, and final health outcomes.
- To determine the utility of a theory-driven evaluation model.
Main Methods:
- Quasi-experimental study with 189 COPD patients in Dutch primary care.
- 12-month follow-up including patient education and structured nurse coordination.
- Data collected on intermediate outcomes (knowledge, self-efficacy) and final outcomes (dyspnea, quality of life).
Main Results:
- Significant improvements observed in dyspnea and patient experiences (p < 0.001).
- No significant improvement in mean quality of life scores (CRQ, CCQ).
- Intermediate outcomes like disease-specific knowledge and medication compliance improved significantly.
Conclusions:
- Theory-driven models enhance the design and evaluation of disease management programs.
- A theoretical approach strengthens evaluation designs for complex interventions.
- COPD management programs positively influence patient outcomes of care.
Related Concept Videos
Chronic Obstructive Pulmonary Disease-V: Management
Smoking Cessation
Chronic Obstructive Pulmonary Disease-V: Nursing Management
Assessment
COPD: Management Using Bronchodilators and Corticosteroids
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
Medical History
Chronic Obstructive Pulmonary Disease-I: Introduction
COPD: Pathogenesis and Clinical Features
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...