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Using Optical Coherence Tomography and Optokinetic Response As Structural and Functional Visual System Readouts in Mice and Rats
Published on: January 10, 2019
Optical small animal imaging in the drug discovery process
Abstract:
Molecular imaging of tumors in preclinical models is of the utmost importance for developing innovative cancer treatments. This field is moving extremely rapidly, with recent advances in optical imaging technologies and sophisticated molecular probes for in vivo imaging. The aim of this review is to provide a succinct overview of the imaging modalities available for rodents and with focus on describing optical probes for cancer imaging.
Insights
This review covers optical imaging techniques and molecular probes for preclinical cancer research. It highlights advances in rodent tumor imaging for developing new cancer therapies.
Area of Science:
- Oncology
- Biomedical Imaging
- Preclinical Research
Background:
- Molecular imaging is crucial for advancing cancer treatment development.
- Rapid progress in optical imaging technologies and molecular probes is transforming in vivo studies.
- Rodent models are essential for evaluating novel cancer therapies.
Purpose of the Study:
- To provide an overview of rodent imaging modalities for cancer research.
- To focus on optical probes utilized in preclinical cancer imaging.
- To summarize recent advancements in molecular imaging for oncology.
Main Methods:
- Review of current literature on optical imaging techniques.
- Analysis of molecular probes for in vivo tumor detection.
- Focus on modalities applicable to rodent models.
Main Results:
- Identification of key optical imaging modalities for preclinical cancer studies.
- Description of various molecular probes and their applications.
- Highlighting the importance of in vivo imaging in drug development.
Conclusions:
- Optical imaging and molecular probes are vital tools in preclinical cancer research.
- Continued innovation in this field accelerates the development of novel cancer treatments.
- Rodent models provide a critical platform for translating imaging advancements.
