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A System for Tracking the Dynamics of Social Preference Behavior in Small Rodents
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Genetics of human social behavior.

Richard P Ebstein1, Salomon Israel, Soo Hong Chew

  • 1Department of Psychology, The Hebrew University of Jerusalem, Jerusalem 91905, Israel. rpebstein@gmail.com

Neuron
|March 30, 2010
PubMed
Summary

Human social behaviors like empathy and trust are partially hardwired, with specific genes like the oxytocin receptor playing a key role. Research is uncovering the genetic basis of our complex social nature.

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Area of Science:

  • Neuroscience
  • Behavioral Genetics
  • Evolutionary Psychology

Background:

  • Humans are highly social, exhibiting complex cooperative behaviors comparable to eusocial insects.
  • Twin and family studies indicate a genetic component to human social traits like empathy, altruism, and trust.
  • Understanding the genetic underpinnings of social behavior has advanced with insights from mammalian studies.

Purpose of the Study:

  • To explore the genetic basis of uniquely human social behaviors.
  • To identify specific genes involved in the "social brain."
  • To connect findings from lower mammal social behavior research to human genetics.

Main Methods:

  • Review of twin and family studies on human social traits.
  • Analysis of genetic research on social behavior in mammals, including voles.
  • Examination of genes related to neurotransmitter pathways (dopamine, serotonin) and hormones.

Main Results:

  • Genes like the arginine vasopressin receptor and oxytocin receptor are crucial for social behavior across species.
  • Polymorphic genes in dopamine reward pathways, serotonin regulation, and sex hormones also contribute significantly.
  • These genetic factors provide a biological basis for complex human social interactions.

Conclusions:

  • Human sociality has a significant, partially hardwired genetic component.
  • Specific genes, notably those for oxytocin and vasopressin receptors, are key regulators of social behavior.
  • Further research into these genes can illuminate the evolution and mechanisms of human sociality.