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Published on: September 1, 2018
Jacks of all trades?--Probably not. The E. coli Eib proteins bind IgG Fc
1Macromolecular Crystallography Group, Structural Biology and Biophysics, Institute of Biotechnology, Abo Akademi University, 20520 Turku, Finland.
Abstract:
We recently published a paper in Molecular Immunology (Leo and Goldman, 2009) showing that the Eib proteins from certain E. coli strains bind IgG Fc, in contrast to a previous report (Ghumra and Pleass, 2007). Richard J. Pleass has commented on our paper (Pleass, 2009) and expressed a series of unjustified misgivings about our conclusions. Here, we address the points raised by Pleass, and reassert our claim that the Eibs are indeed genuine receptors for IgG Fc.
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