Related Experiment Video
Updated: Jun 14, 2026

08:07
Paradigms of Lower Extremity Electrical Stimulation Training After Spinal Cord Injury
Published on: February 1, 2018
Skeletal and body composition changes in hemiplegic patients
Olga Lazoura1, Paraskevi J Papadaki, Eleftheria Antoniadou
1Department of Radiology, National Rehabilitation Centre, Athens, Greece.
Summary
Stroke survivors with hemiplegia experience significant bone density loss and changes in body composition within the first year post-stroke. These changes increase their risk of fractures and impact rehabilitation.
Area of Science:
- Rehabilitation Medicine
- Bone Metabolism
- Body Composition Analysis
Background:
- Hemiplegic patients face risks of bone loss and altered body composition.
- These changes negatively impact rehabilitation outcomes and fracture risk.
Purpose of the Study:
- To evaluate body composition and bone mineral density (BMD) in hemiplegic stroke patients.
- Assess changes within the first 12 months post-stroke.
Main Methods:
- Prospective study of 58 hemiplegic patients (36 men, 22 women).
- Dual-energy X-ray absorptiometry (DXA) for BMD, lean mass, and fat mass.
- Modified Ashworth Scale and functional ambulation category used for spasticity and mobility assessment.
Main Results:
- Both sexes showed decreased BMD in total body and paretic lower limb.
- Significant fat mass gain and lean mass loss observed.
- Changes were most pronounced between 3 and 6 months post-stroke, with variations between sexes.
Conclusions:
- Hemiplegia-induced disability alters muscle function, leading to skeletal and body composition changes.
- These alterations heighten the risk of fractures in stroke survivors.
- Targeted interventions may be necessary to mitigate these risks.
Related Concept Videos
Alterations in Muscle Tone ll
Alterations in muscle tone are common manifestations of neurological disorders and reflect dysfunction within different nervous system regions. Spasticity, paratonia, and dystonia represent distinct forms of hypertonia, each with unique mechanisms, clinical features, and diagnostic importance.CharacteristicsSpasticity happens from upper motor neuron lesions and is characterized by velocity-dependent resistance to passive movement. Clinical features include:Exaggerated deep tendon reflexesClonus...
Alterations in Muscle Tone lll
Rigidity and myotonia are distinct abnormalities of muscle tone that affect resistance and relaxation during movement. Although both involve altered muscle contraction, they arise from different neurological and muscular mechanisms.CharacteristicsRigidity is characterized by uniform resistance to passive movement across the entire range, independent of speed, affecting flexors and extensors equally. It may appear as lead-pipe rigidity (smooth, constant resistance) or cogwheel rigidity...
Changes in the Appendicular Skeleton with Age
The upper and lower limb initially develops as a small bulge called a limb bud, which appears on the lateral side of the early embryo. The upper limb bud appears near the end of the fourth week of development, with the lower limb bud appearing shortly after.
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
