Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 14, 2026

Assessment and Communication for People with Disorders of Consciousness
07:37

Assessment and Communication for People with Disorders of Consciousness

Published on: August 1, 2017

Towards a user-friendly brain-computer interface: initial tests in ALS and PLS patients.

Ou Bai1, Peter Lin, Dandan Huang

  • 1EEG & BCI Laboratory, Department of Biomedical Engineering, Virginia Commonwealth University, Richmond, VA 23284, USA. obai@vcu.edu

Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology
|March 30, 2010
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Quality assessment and hydrochemical control mechanism of groundwater in the Hailar Basin.

Environmental geochemistry and health·2026
Same author

Steering Peroxymonosulfate Activation Toward Exclusive Singlet Oxygen Generation via Active Iron Carbides Nanoparticles.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same author

Corrigendum to "Electrically enhanced, Nature-Driven microbial attenuation of chromate and dichloromethane in groundwater" [Bioresour. Technol. 459 (2026) 135175].

Bioresource technology·2026
Same author

Icariside Ⅱ alleviates heart failure based on Wnt/β-catenin-mitochondrial apoptotic pathway.

European journal of pharmacology·2026
Same author

Seasonal Variability and Atmospheric Drivers of Particle-Phase PFAS in PM<sub>2.5</sub> near a Municipal Solid Waste Incineration Facility in Nanchang, China.

Environmental pollution (Barking, Essex : 1987)·2026
Same author

Systematic review and meta-analysis of balance training in children with developmental disorders.

PeerJ·2026

Patients with ALS or PLS can achieve brain-computer interface (BCI) control with minimal training. This user-friendly BCI reduces mental load and fatigue, promoting practical applications for paralyzed individuals.

Area of Science:

  • Neuroscience
  • Rehabilitation Engineering

Background:

  • Effective brain-computer interface (BCI) control typically requires extensive patient training.
  • Prolonged BCI use leads to fatigue due to sustained focused attention.
  • Developing user-friendly BCIs with reduced mental load is crucial for practical applications.

Purpose of the Study:

  • To develop and evaluate a user-friendly BCI system for patients with amyotrophic lateral sclerosis (ALS) and primary lateral sclerosis (PLS).
  • To minimize training time and mental exertion associated with BCI operation.
  • To investigate BCI control using natural motor behavior paradigms.

Main Methods:

  • Three ALS and three PLS patients with no prior BCI experience participated.
  • Patients performed binary or four-directional cursor control using motor execution and motor imagery.

More Related Videos

Brain-Computer Interface-controlled Upper Limb Robotic System for Enhancing Daily Activities in Stroke Patients
06:11

Brain-Computer Interface-controlled Upper Limb Robotic System for Enhancing Daily Activities in Stroke Patients

Published on: April 18, 2025

Eye-Tracking Control to Assess Cognitive Functions in Patients with Amyotrophic Lateral Sclerosis
07:00

Eye-Tracking Control to Assess Cognitive Functions in Patients with Amyotrophic Lateral Sclerosis

Published on: October 13, 2016

Related Experiment Videos

Last Updated: Jun 14, 2026

Assessment and Communication for People with Disorders of Consciousness
07:37

Assessment and Communication for People with Disorders of Consciousness

Published on: August 1, 2017

Brain-Computer Interface-controlled Upper Limb Robotic System for Enhancing Daily Activities in Stroke Patients
06:11

Brain-Computer Interface-controlled Upper Limb Robotic System for Enhancing Daily Activities in Stroke Patients

Published on: April 18, 2025

Eye-Tracking Control to Assess Cognitive Functions in Patients with Amyotrophic Lateral Sclerosis
07:00

Eye-Tracking Control to Assess Cognitive Functions in Patients with Amyotrophic Lateral Sclerosis

Published on: October 13, 2016

  • Short practice sessions (5-10 min) were followed by 1.5-2 hour multi-session studies.

    • Main Results:

    • All patients exhibited event-related desynchronization/synchronization in the beta band.
    • Online binary control accuracy averaged ~80-82% (motor execution/imagery).
    • Four-directional control accuracy ranged from 50-60%.

    Conclusions:

    • ALS and PLS patients can achieve BCI control without prolonged training.
    • BCIs aligned with natural motor behavior may reduce operational fatigue.
    • User-friendly BCIs can enhance practical applications for paralyzed individuals.