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Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Fungal Group Zygomycota01:29

Fungal Group Zygomycota

Zygomycota, previously classified as a distinct fungal group, are primarily terrestrial, saprophytic molds that play a crucial role as decomposers. Recent phylogenetic studies have revealed that these fungi are now divided into two major clades — Mucoromycota, which includes many symbiotic species, and Zoopagomycota, which primarily consists of parasitic and pathogenic fungi. These groups exhibit distinct ecological roles and reproductive strategies while sharing key structural and...
Fungal Phylum Basidiomycota01:26

Fungal Phylum Basidiomycota

Basidiomycota is a diverse phylum of fungi that includes ecologically significant decomposers such as white rot fungi, symbionts like mycorrhizal fungi, plant pathogens such as rusts and smuts, and edible species like Agaricus bisporus (the common button mushroom). These fungi play crucial roles in nutrient cycling, symbiotic relationships, and even human health. Their defining feature is the basidium, a microscopic club-shaped structure responsible for producing basidiospores.Fruiting Bodies...
Antifungal Agents01:15

Antifungal Agents

Amphotericin B is a broad-spectrum antifungal agent that exploits structural differences between fungal and mammalian cell membranes. Its amphipathic structure—featuring a hydrophobic polyene-lactone ring and a hydrophilic region containing mycosamine and carboxylic acid groups—enables selective binding to ergosterol, a sterol predominantly found in fungal plasma membranes. This selective interaction underlies the drug’s antifungal activity, although weak binding to cholesterol contributes to...
Fungal Phylum Microsporidia01:28

Fungal Phylum Microsporidia

Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
Fungal Phylum Ascomycota01:28

Fungal Phylum Ascomycota

Phylum Ascomycota, a major division within the subkingdom Dikarya, comprises a diverse range of fungal species, including both unicellular yeasts and filamentous molds such as Aspergillus and Penicillium. These fungi thrive in a variety of habitats, from aquatic ecosystems to terrestrial environments, playing crucial ecological and economic roles.Morphology and ReproductionThe defining characteristic of Ascomycetes, commonly referred to as sac fungi, is the ascus—a sac-like structure that...

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Related Experiment Video

Updated: Jun 14, 2026

Bio-energetics Investigation of Candida albicans Using Real-time Extracellular Flux Analysis
08:48

Bio-energetics Investigation of Candida albicans Using Real-time Extracellular Flux Analysis

Published on: March 19, 2019

Other fungi causing onychomycosis.

Gabriela Moreno1, Roberto Arenas

  • 1Mycology Section, Department of Dermatology, Dr. Manuel Gea Gonzalez General Hospital, Calzada de Tlalpan 4800, 14080 México, DF, México.

Clinics in Dermatology
|March 30, 2010
PubMed
Summary

Nondermatophyte onychomycosis, a fungal nail infection, is caused by various fungi. Accurate diagnosis requires specific criteria due to potential lab contamination.

Area of Science:

  • Mycology
  • Dermatology
  • Infectious Diseases

Background:

  • Nondermatophyte onychomycosis constitutes 2-12% of all nail fungal infections.
  • Common causative agents include Scopulariopsis, Aspergillus, Fusarium, and Scytalidium species.
  • Predisposing factors include hyperhidrosis, trauma, and immunosuppression.

Purpose of the Study:

  • To review the characteristics and diagnosis of nondermatophyte onychomycosis.
  • To highlight the diagnostic challenges posed by nondermatophyte fungi.
  • To outline clinical presentations and diagnostic criteria.

Main Methods:

  • Literature review of nondermatophyte onychomycosis.
  • Analysis of causative agents and predisposing factors.
  • Discussion of diagnostic criteria and clinical manifestations.

Related Experiment Videos

Last Updated: Jun 14, 2026

Bio-energetics Investigation of Candida albicans Using Real-time Extracellular Flux Analysis
08:48

Bio-energetics Investigation of Candida albicans Using Real-time Extracellular Flux Analysis

Published on: March 19, 2019

Main Results:

  • Nondermatophyte fungi, unlike dermatophytes, have limited keratinolytic capacity.
  • These fungi can cause onychomycosis independently or concurrently with dermatophytes.
  • Superficial onychomycosis, leukonychia, and melanonychia are common clinical presentations.

Conclusions:

  • Specialized diagnostic criteria are essential for nondermatophyte onychomycosis.
  • Accurate identification of the etiologic agent is crucial for appropriate management.
  • Understanding predisposing factors aids in prevention and treatment strategies.