Related Experiment Video
Updated: Jun 14, 2026

06:39
Curcuminoid-Mediated Antimicrobial Photodynamic Therapy on a Murine Model of Oral Candidiasis
Published on: October 27, 2023
Diseases mimicking onychomycosis
1Department of Dermatology, Universidad de Buenos Aires, UBA, Paraguay 2345, CABA (1121), Buenos Aires, Argentina. miguelallevato@fibertel.com.ar
Clinics in Dermatology
|March 30, 2010
Summary
Onychodystrophy diagnoses are rising in dermatology. Onychomycosis is a common cause, identified in 50% of cases, making it a key differential diagnosis for nail conditions.
Area of Science:
- Dermatology
- Mycology
Background:
- The incidence of onychodystrophy diagnoses has increased in dermatological consultations.
- Potential contributing factors include aesthetic concerns, pain, disability, increased physician awareness, and a higher disease prevalence.
Purpose of the Study:
- To highlight the importance of considering onychomycosis in the differential diagnosis of onychodystrophy.
- To underscore the prevalence of fungal infections as a cause of nail dystrophy.
Main Methods:
- Review of dermatological consultation data.
- Analysis of differential diagnoses for onychodystrophic nails.
Main Results:
- Onychomycosis is a primary consideration for onychodystrophy.
- Fungal infections account for 50% of onychodystrophy cases.
Conclusions:
- Early and accurate diagnosis of onychomycosis is crucial for managing onychodystrophy.
- Onychomycosis should be a leading differential diagnosis for all onychodystrophic nail presentations.
Related Concept Videos
Skin Diseases and Disorders
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Candidiasis
Candidiasis is a fungal infection caused by opportunistic species of Candida. It can affect various anatomical sites, including the skin, oral cavity, nails, and genitourinary tract. Among its forms, vaginal candidiasis is the most common type of mucosal infection. It typically results from the overgrowth of Candida albicans in the vaginal mucosa. Under normal conditions, C. albicans exists as a commensal organism within the vaginal microbiota, regulated by the dominance of lactobacilli, which...
Antifungal Agents
Amphotericin B is a broad-spectrum antifungal agent that exploits structural differences between fungal and mammalian cell membranes. Its amphipathic structure—featuring a hydrophobic polyene-lactone ring and a hydrophilic region containing mycosamine and carboxylic acid groups—enables selective binding to ergosterol, a sterol predominantly found in fungal plasma membranes. This selective interaction underlies the drug’s antifungal activity, although weak binding to cholesterol contributes to...
Fungal Phylum Microsporidia
Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
Fungal Group Zygomycota
Zygomycota, previously classified as a distinct fungal group, are primarily terrestrial, saprophytic molds that play a crucial role as decomposers. Recent phylogenetic studies have revealed that these fungi are now divided into two major clades — Mucoromycota, which includes many symbiotic species, and Zoopagomycota, which primarily consists of parasitic and pathogenic fungi. These groups exhibit distinct ecological roles and reproductive strategies while sharing key structural and...
Endocarditis II: Clinical Features of Infective Endocarditis
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...