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Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Antifungal Agents01:15

Antifungal Agents

Amphotericin B is a broad-spectrum antifungal agent that exploits structural differences between fungal and mammalian cell membranes. Its amphipathic structure—featuring a hydrophobic polyene-lactone ring and a hydrophilic region containing mycosamine and carboxylic acid groups—enables selective binding to ergosterol, a sterol predominantly found in fungal plasma membranes. This selective interaction underlies the drug’s antifungal activity, although weak binding to cholesterol contributes to...
Candidiasis01:20

Candidiasis

Candidiasis is a fungal infection caused by opportunistic species of Candida. It can affect various anatomical sites, including the skin, oral cavity, nails, and genitourinary tract. Among its forms, vaginal candidiasis is the most common type of mucosal infection. It typically results from the overgrowth of Candida albicans in the vaginal mucosa. Under normal conditions, C. albicans exists as a commensal organism within the vaginal microbiota, regulated by the dominance of lactobacilli, which...
Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
Fungal Group Zygomycota01:29

Fungal Group Zygomycota

Zygomycota, previously classified as a distinct fungal group, are primarily terrestrial, saprophytic molds that play a crucial role as decomposers. Recent phylogenetic studies have revealed that these fungi are now divided into two major clades — Mucoromycota, which includes many symbiotic species, and Zoopagomycota, which primarily consists of parasitic and pathogenic fungi. These groups exhibit distinct ecological roles and reproductive strategies while sharing key structural and...
Fungal Phylum Ascomycota01:28

Fungal Phylum Ascomycota

Phylum Ascomycota, a major division within the subkingdom Dikarya, comprises a diverse range of fungal species, including both unicellular yeasts and filamentous molds such as Aspergillus and Penicillium. These fungi thrive in a variety of habitats, from aquatic ecosystems to terrestrial environments, playing crucial ecological and economic roles.Morphology and ReproductionThe defining characteristic of Ascomycetes, commonly referred to as sac fungi, is the ascus—a sac-like structure that...

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Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses
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Published on: June 13, 2018

Superficial veterinary mycoses.

Ross Bond1

  • 1Department of Veterinary Clinical Studies, Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, Herts AL9 7TA, United Kingdom. rbond@rvc.ac.uk

Clinics in Dermatology
|March 30, 2010
PubMed
Summary
This summary is machine-generated.

Dermatophytes and Malassezia species are key veterinary skin pathogens. This chapter details their epidemiology, clinical signs, diagnosis, and treatment in animals, focusing on significant superficial mycoses.

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Area of Science:

  • Veterinary Mycology
  • Dermatology
  • Zoonotic Diseases

Background:

  • Dermatophytes and Malassezia species are significant superficial fungal pathogens in veterinary medicine.
  • Dermatophytes pose zoonotic risks and cause economic losses in livestock and fur animals, as well as skin lesions in pets.
  • Malassezia species, particularly Malassezia pachydermatis, are common causes of otitis and dermatitis in dogs.

Purpose of the Study:

  • To provide a comprehensive overview of dermatophytosis and Malassezia dermatitis in veterinary species.
  • To detail the epidemiologic, clinical, diagnostic, and therapeutic aspects of these fungal infections.
  • To differentiate the significance and impact of dermatophytes versus Malassezia species in animal health.

Main Methods:

  • Review of existing literature on dermatophytosis and Malassezia infections in veterinary species.
  • Synthesis of information regarding epidemiology, pathogenesis, clinical presentation, diagnosis, and treatment.
  • Focus on companion and farm animals, excluding rarer superficial mycoses.

Main Results:

  • Dermatophytes and Malassezia species differ in their epidemiology, pathogenesis, and clinical outcomes.
  • Dermatophytosis has significant zoonotic potential and economic impact.
  • Malassezia pachydermatis is a prevalent cause of otitis and dermatitis in dogs.

Conclusions:

  • Dermatophytosis and Malassezia dermatitis are the most important superficial mycoses in veterinary medicine.
  • Understanding the distinct characteristics of these fungi is crucial for effective management.
  • This chapter serves as a focused resource on these significant animal fungal diseases.