[Patterns in the formation of cerebral damage and recovery from supralethal irradiation]

In experiments with rats it has been shown that dose-rate and radiation fractionation influence the dose dependence of early transient incapacity (ETI) and the development of tolerance to ETI. The authors discuss the possibility of interpreting the tolerance to ETI as a form of the cerebral damage displayed by the impairment of the brain response to radiation. A correlation has been revealed between the cerebral damage and recovery and repair of radiogenic damages to DNA.