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Updated: Aug 11, 2026

Quantifying Cognitive Decrements Caused by Cranial Radiotherapy
Published on: October 18, 2011
[Effect of a high-intensity radiation exposure on brain function in monkeys. Postradiation changes in central
Abstract:
In experiments with Macaca fascicularis exposed to high-energy electrons (45 Gy, 6.5 Gy/s) revealed were early changes in the coherent spectrum of EEG semihemispheric leads. These changes were displayed by the increased interrelation between slow-wave fluctuations and decreased coherence within the mid- and high-frequency EEG-rhythms band. The relationship was noted between the changes observed and the clinical symptoms features of early radiation response as well as the dynamics of the CNS functions of exposed animals. Postirradiation changes in the intracellular bioelectric interaction are considered as one of the manifestations of the systemic response of the brain to the harmful effect of radiation.
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