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Leishmaniasis in the tongue of an immunocompetent man
Verena Leitner1, Jessika Weingast, Kaan Harmankaya
1Department of Dermatology, Medical University of Vienna, Vienna, Austria. verena.leitner@meduniwien.ac.at
Abstract:
A 49-year-old immunocompetent white man had a painful ulcer (1.5 cm in diameter) on the left ventrolateral surface of a grossly enlarged tongue. The ulcer was present for two months. Impaired swallowing resulted in substantial weight loss and fatigue. Histopathologic analysis of a punch biopsy specimen indicated numerous Leishman Donovan bodies within macrophages. A polymerase chain reaction confirmed the presence of L. donovani. Therapy with two cycles of liposomal amphotericin B over a three-month period was administered. Four months after discharge, the ulcer had healed completely and the tongue returned to its normal size and function.
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