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Published on: December 8, 2015
Titanium compacts produced by the pulvimetallurgical hydride-dehydride method for biomedical applications
M M Barreiro1, D R Grana, G A Kokubu
1Universidad de Buenos Aires, Argentina. mbarreiro@mater.odon.uba.ar
Biomedical Materials (Bristol, England)
|March 30, 2010
Summary
The hydride-dehydride method offers a cost-effective way to produce titanium powder. This study found no significant differences in compactation, sintering, or biocompatibility compared to commercially produced titanium powder.
Area of Science:
- Materials Science
- Biomaterials Engineering
Background:
- Titanium powder is crucial for biomedical implants.
- Current production methods can be expensive.
- The hydride-dehydride (HDH) process offers a potentially lower-cost alternative.
Purpose of the Study:
- To evaluate the efficacy of the hydride-dehydride method for producing titanium powder.
- To compare HDH-produced titanium powder with commercially available titanium powder.
- To assess the biocompatibility of titanium derived from the HDH process.
Main Methods:
- Commercially pure grade two titanium was hydrogenated and milled.
- The hydrided powder was dehydrided and sieved to a particle size of 37–125 µm.
- Powders were uniaxially pressed into compacts and sintered in a vacuum.
- Characterization included powder analysis, density measurements, oxygen content, and in vivo biocompatibility tests in Wistar rats.
Main Results:
- Titanium powder was successfully produced via the HDH method with controlled particle size.
- No significant differences were observed in compactation behavior between HDH and commercial powders.
- Sintering characteristics and the density of sintered compacts were comparable.
- In vivo biocompatibility tests showed no adverse effects or differences between the two powder types.
Conclusions:
- The hydride-dehydride method is a viable and cost-effective route for titanium powder production.
- Titanium powder produced by HDH exhibits comparable properties and biocompatibility to commercial titanium powder.
- This HDH process holds promise for reducing the cost of titanium-based biomaterials.

