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Personalized Peptide Arrays for Detection of HLA Alloantibodies in Organ Transplantation

Personalized Peptide Arrays for Detection of HLA Alloantibodies in Organ Transplantation

Published on: September 6, 2017

An update to HLA nomenclature, 2010.

S G E Marsh¹, E D Albert, W F Bodmer

¹Anthony Nolan Research Institute, London, UK. steven.marsh@ucl.ac.uk

Bone Marrow Transplantation

|March 30, 2010

Summary

The World Health Organization Nomenclature Committee for Factors of the HLA System updated human leukocyte antigen (HLA) nomenclature. This report details additions and revisions to HLA specificities based on established principles.

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Area of Science:

Immunogenetics
Molecular Biology
Genetics

Background:

The Human Leukocyte Antigen (HLA) system is crucial for immune response and transplantation.
Accurate HLA nomenclature is essential for clinical practice and research.
Previous reports established principles for updating HLA gene and protein naming.

Purpose of the Study:

To document additions and revisions to the human leukocyte antigen (HLA) nomenclature.
To present updates following the 15th International Histocompatibility and Immunogenetics Workshop.
To maintain consistency and accuracy in HLA specificity reporting.

Main Methods:

The WHO Nomenclature Committee for Factors of the HLA System convened in September 2008.
The committee reviewed data and applied established nomenclature principles.
This work is an extract from the main report of the workshop.

Main Results:

New additions and revisions to HLA specificities were documented.
The nomenclature for various HLA factors was updated.
The report provides a comprehensive overview of the nomenclature changes.

Conclusions:

The updated HLA nomenclature ensures accurate communication in immunogenetics.
Regular updates are vital for reflecting advancements in HLA typing.
This revision supports ongoing research and clinical applications in transplantation and disease association studies.