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Published on: June 16, 2020
Pulmonary CT findings in relapsing polychondritis
Zhi Qian Lin1, Jian Rong Xu, Jie Jun Chen
1Department of Radiology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Computed tomography (CT) revealed significant airway abnormalities in relapsing polychondritis (RPC) patients. Findings included airway wall thickening, stenosis, malacia, calcification, and air trapping, impacting respiratory health.
Area of Science:
- Radiology
- Rheumatology
- Pulmonology
Background:
- Relapsing polychondritis (RPC) is a rare rheumatic disease.
- Characterized by recurrent inflammation of cartilaginous structures.
- Airway involvement is a significant cause of morbidity and mortality in RPC.
Purpose of the Study:
- To retrospectively evaluate airway and lung abnormalities in relapsing polychondritis (RPC).
- Utilized computed tomography (CT) for imaging assessment.
Main Methods:
- Retrospective analysis of chest CT examinations from 21 RPC patients (2004-2009).
- Two radiologists evaluated CT images for abnormalities.
- Noted findings included airway stenosis, malacia, air trapping, and wall thickening/calcification.
Main Results:
- 38.1% of patients showed major CT abnormalities.
- Common findings: airway wall thickening (7), stenosis (6), malacia (6), calcification (8), and air trapping (3).
- Additional findings included mediastinal lymph nodes (12), lung infection (4), and interstitial lung disease (6).
Conclusions:
- CT findings in RPC predominantly involve airway abnormalities.
- Key CT findings include airway wall thickening, stenosis, malacia, calcification, and air trapping.
- These findings are crucial for understanding and managing respiratory complications in RPC.
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