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Updated: Jun 14, 2026

Studying Orthodontic Tooth Movement in Mice
Published on: August 2, 2024
The fundamentals of tooth movement
Michel Le Gall1, Julien Sastre
1Faculté d'odontologie de Marseille, hôpital de La Timone, Marseille, France. msjlegall@aol.com
Abstract:
Advances in the field of molecular phenomena have led to a fuller understanding of the mechanisms at work in tooth movement. The forces applied by orthodontic devices are converted into cellular signals via the deformation of the bony walls and the inflammatory reaction they trigger. In turn, the numerous cytokines, which are created by this process activate other messengers which differentiate, activate and inhibit the different cell populations involved in tooth movement.
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