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Related Experiment Videos

Polymicrobial bacteremia during long-term hemodialysis.

L L Mulloy1, R J Caruana, J C Steele

  • 1Department of Medicine, Medical College of Georgia, Augusta 30912.

Southern Medical Journal
|May 1, 1991
PubMed
Summary

Long-term hemodialysis patients are at increased risk for polymicrobial bacteremia, often linked to vascular access devices. Prompt removal of devices and antibiotic treatment are crucial for recovery.

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Area of Science:

  • Nephrology
  • Infectious Diseases
  • Hospital Epidemiology

Background:

  • Polymicrobial bacteremia presents a significant challenge in hospital settings.
  • Patients undergoing long-term hemodialysis are a vulnerable population for infections.

Purpose of the Study:

  • To investigate the occurrence and characteristics of polymicrobial bacteremia in hemodialysis patients.
  • To identify risk factors and outcomes associated with these infections.

Main Methods:

  • Review of hospital epidemiologic data over a 30-month period.
  • Analysis of five cases of polymicrobial bacteremia on a nephrology inpatient service.
  • Examination of patient history, including dialysis status and vascular access devices.

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Main Results:

  • Five cases of polymicrobial bacteremia were identified in long-term hemodialysis patients.
  • Four out of five patients had indwelling silicone rubber vascular access devices.
  • No obvious skin or visceral infection was noted in any patient.
  • One patient died; four recovered after device removal and antibiotic therapy.

Conclusions:

  • Long-term hemodialysis is associated with an increased risk of polymicrobial bacteremia.
  • Indwelling vascular access devices may play a role in the pathogenesis of these infections.
  • Empiric antibiotic therapy should consider the risk of polymicrobial bacteremia in hemodialysis patients.