Related Experiment Video
Updated: Jun 14, 2026

Assessment of Physical Activity Intensity with Accelerometers and Oxygen Consumption
Published on: June 20, 2025
Walking and running economy: inverse association with peak oxygen uptake
Brandon J Sawyer1, Jason R Blessinger, Brian A Irving
1Department of Kinesiology, Point Loma Nazarene University, San Diego, CA, USA. bjsawyer@asu.edu
Purpose:
The purpose of this study was to test the hypothesis that V˙O2peak is positively correlated with the regression coefficients of the curve-linear relationship between V˙O2 and speed during a protocol consisting of submaximal walking and running.
Methods:
Nineteen healthy men (mean ± SD: age = 26.4 ± 6.4 yr, height = 179.9 ± 7.2 cm, weight = 77.7 ± 8.7 kg, % fat = 16.3 ± 7.3) and 21 healthy women (age = 25.6 ± 4.9 yr, height = 167.2 ± 5.4 cm, weight = 61.6 ± 7.7 kg, % fat = 24.0 ± 6.8) underwent an incremental treadmill test to determine VO2peak and on two separate days performed an exercise protocol consisting of treadmill walking on a level grade at 2.0 mph (54 m·min−¹), 3.0 mph (80 m·min−¹), and 4.0 mph (107 m·min−¹) and running at 6.0 mph (161 m·min−¹). Subjects exercised for 5 min at each velocity, with 3 min of rest in between each exercise bout. Pulmonary ventilation (VE) and gas exchange were measured breath-by-breath each minute. The average of VO2 values obtained during the last 2 min of exercise for both exercise sessions was used in polynomial random coefficient regression analysis.
Results:
In the polynomial random coefficient regression analysis for walking speeds only, both linear (r = 0.31, P = 0.053) and quadratic (r = 0.35, P = 0.029) coefficients were modestly correlated with VO2peak. Steady-state VO2 during walking at 3.0 and 4.0 mph and running at 6.0 mph was also modestly correlated with VO2peak (r = 0.30-0.48).
Conclusions:
The results confirm our hypothesis and suggest that, as walking speed increases, the increase in VO2 is positively correlated with the VO2peak. Our findings are consistent with the notion that cardiorespiratory fitness and exercise economy are inversely related.
Related Concept Videos
Metabolic Rate
The Basal Metabolic Rate (BMR) measures the energy expended at rest.
Several factors influence the...
Exercise and Cardiac Output
Sustained exercise increases the muscles' oxygen demand, which can be met...
Factors Affecting Respiration
Exercise and Cardiovascular Response
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Oxygen Transport in the Blood
Cardiac Output I:Effect of Heart Rate on Cardiac Output
Cardiac output (CO) refers to the total amount of blood ejected by one of the ventricles in liters per minute (L/min). In a resting adult, CO ranges from 5 to 6 L/min, adjusting according to the body's metabolic requirements.
Effect of Heart Rate on Cardiac Output
Cardiac output adapts to metabolic demands during stress, physical activity, or illness. The autonomic nervous system regulates heart rate via the sinoatrial node. The parasympathetic nervous system decreases heart rate...
