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Fabrication of a Bioactive, PCL-based "Self-fitting" Shape Memory Polymer Scaffold
Published on: October 23, 2015
Combined solid/solution phase synthesis of large surface area scaffolds derived from aminomethyl-benzoates
Rishi K Jain1, Lun K Tsou, Andrew D Hamilton
1Department of Chemistry, Yale University, New Haven, CT 06520, U.S.A.
Tetrahedron Letters
|March 31, 2010
Abstract:
A set of macrocycles was generated by solid phase synthesis of linear trimers of 5-aminoacyl-3-aminomethyl-benzoates followed by resin cleavage and solution phase macrocyclization. These scaffolds can serve as useful building blocks for molecular recognition studies, especially where differentially functionalized molecular platforms spanning large surface areas are required.
