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Hyaluronic acid in a cardiac myxoma: a biochemical and histological analysis
M T Longaker1, E S Chiu, B Hendin
1Department of Surgery, University of California, San Francisco 94143.
Virchows Archiv. A, Pathological Anatomy and Histopathology
|January 1, 1991
Abstract:
Cardiac myxoma is the most common primary tumor of the heart. This tumor has a gelatinous stroma that is thought to be composed of glycosaminoglycans, the classical acid mucopolysaccharide ground substance. We examined both biochemically and histologically the hyaluronic acid in a case of cardiac myxoma using a newly developed hyaluronic acid-binding protein probe. We observed that hyaluronic acid was localized in the amorphous stroma and occurred at levels 30 times that found in normal atrial septum.