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Decreased renal clearance of sodium in cystic fibrosis
P Stenvinkel1, L Hjelte, G Alván
1Department of Nephrology, Karolinska Institute, Huddinge University Hospital, Sweden.
Acta Paediatrica Scandinavica
|February 1, 1991
Abstract:
In 10 patients with cystic fibrosis (CF) and 10 controls of similar age quantitative segmental handling of sodium was estimated by lithium clearance. In the CF group, there was a tendency for an increased glomerular filtration rate (GFR) and increased absolute proximal sodium reabsorption. The fractional distal sodium reabsorption was significantly (p = 0.015) increased and sodium clearance was significantly (p less than 0.01) decreased in CF.