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Published on: September 12, 2019
Cytogenetics of endometrial adenocarcinoma
G Horgas1, G Grubisić, V Lokner
1Nuclear Medicine and Oncology Department, Dr Mladen Stojanović University Hospital, Zagreb.
Abstract:
The results of karyotypic analysis of a new case of endometrial adenocarcinoma revealed in all analyzed diploid or near-diploid cells two chromosomes 1 of normal morphology and the presence of a marker or markers derived from chromosome 1. No other common chromosome marker was observed. Among a total of 25 endometrial adenocarcinoma cases reported in literature, including the case we reported, the most frequent chromosome abnormality-observed was trisomy and tetrasomy of the long arm of chromosome 1 which may represent a specific karyotypic change in at least one subtype of this tumor.
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