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Updated: Jun 14, 2026
09:14
Surgical Approach to Full Soft Tissue Face Allograft Procurement for Vascularized Composite Allotransplantation
Published on: December 30, 2025
Overview of guidelines for establishing a face transplant program: a work in progress
1Department of Plastic Surgery, Cleveland Clinic, Cleveland, OH, USA.
Summary
Face transplantation is an experimental procedure with encouraging short-term outcomes. This guide assists medical centers in establishing face transplant programs by detailing logistical challenges and requirements for success.
Area of Science:
- Surgical Innovation
- Transplantation Medicine
Background:
- Nine face transplantations performed globally since 2005.
- Longest survival approaching five years indicates encouraging short-term outcomes.
Purpose of the Study:
- To share experiences and facilitate the establishment of new face transplant programs.
- To provide guidance on logistical challenges and essential requirements for face transplantation.
Main Methods:
- Discussion of logistical challenges including program requirements, protocols, team assembly, funding, and organ procurement.
- Emphasis on the experimental nature and need for validated therapeutic value.
Main Results:
- Identified key logistical considerations for establishing face transplant programs.
- Highlighted the necessity for multidisciplinary teams and long-term commitment.
Conclusions:
- Face transplantation is complex and experimental, requiring careful consideration and validation.
- University-affiliated institutions with specialized multidisciplinary teams are best suited for this procedure.
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