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Updated: Jun 14, 2026

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
Published on: February 7, 2019
A three-dimensional hydrogen-bonded framework in
Lina M Acosta1, Alirio Palma, Ali Bahsas
1Laboratorio de Síntesis Orgánica, Escuela de Química, Universidad Industrial de Santander, AA 678 Bucaramanga, Colombia.
Abstract:
Molecules of the title compound, C(18)H(16)FNO, are linked into a three-dimensional framework structure by a combination of two C-H...O hydrogen bonds and three C-H...pi(arene) hydrogen bonds. Comparisons are made with the (2R,4R) diastereoisomer and with the corresponding pair of diastereoisomeric 7-chloro analogues.
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