Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Understanding the rationale for metronidazole use in dogs and cats.

The Journal of small animal practice·2025
Same author

Genetic therapies for movement disorders - current status.

Journal of neurology·2025
Same author

Quantification of Spatial Ventilation Defect Sparsity in Hyperpolarized Gas Magnetic Resonance Imaging of Lungs Utilizing a Three-Dimensional Clustering Algorithm.

NMR in biomedicine·2025
Same author

Correlation of Inguinal Lymph Node Number and Volume with Lower Extremity Lymphedema Severity.

Lymphology·2024
Same author

Behavioral, metabolic, and lipidomic characterization of the 5xFADxTg30 mouse model of Alzheimer's disease.

iScience·2024
Same author

Laboratory Study of Collisionless Magnetic Reconnection.

Space science reviews·2023

Related Experiment Video

Updated: Jun 14, 2026

Acquiring Hyperpolarized 129Xe Magnetic Resonance Images of Lung Ventilation
09:08

Acquiring Hyperpolarized 129Xe Magnetic Resonance Images of Lung Ventilation

Published on: November 21, 2023

A System for Open-Access He Human Lung Imaging at Very Low Field.

I C Ruset1, L L Tsai, R W Mair

  • 1Department of Physics, University of New Hampshire, Physics Department, 9 Library Way, DeMeritt Hall, Durham, New Hampshire 03824.

Concepts in Magnetic Resonance. Part B, Magnetic Resonance Engineering
|April 1, 2010
PubMed
Summary
This summary is machine-generated.

This study presents a new low-field MRI system for open-access lung imaging using laser-polarized helium-3 (³He) gas, enabling detailed visualization of lung structures.

More Related Videos

Quantitative Mapping of Specific Ventilation in the Human Lung using Proton Magnetic Resonance Imaging and Oxygen as a Contrast Agent
08:26

Quantitative Mapping of Specific Ventilation in the Human Lung using Proton Magnetic Resonance Imaging and Oxygen as a Contrast Agent

Published on: June 5, 2019

Pulmonary Structural MRI using Free-Breathing, Self-Gated Ultra-short Echo Time Imaging
05:07

Pulmonary Structural MRI using Free-Breathing, Self-Gated Ultra-short Echo Time Imaging

Published on: September 6, 2024

Related Experiment Videos

Last Updated: Jun 14, 2026

Acquiring Hyperpolarized 129Xe Magnetic Resonance Images of Lung Ventilation
09:08

Acquiring Hyperpolarized 129Xe Magnetic Resonance Images of Lung Ventilation

Published on: November 21, 2023

Quantitative Mapping of Specific Ventilation in the Human Lung using Proton Magnetic Resonance Imaging and Oxygen as a Contrast Agent
08:26

Quantitative Mapping of Specific Ventilation in the Human Lung using Proton Magnetic Resonance Imaging and Oxygen as a Contrast Agent

Published on: June 5, 2019

Pulmonary Structural MRI using Free-Breathing, Self-Gated Ultra-short Echo Time Imaging
05:07

Pulmonary Structural MRI using Free-Breathing, Self-Gated Ultra-short Echo Time Imaging

Published on: September 6, 2024

Area of Science:

  • Medical Imaging
  • Biophysics
  • Pulmonary Medicine

Background:

  • Magnetic Resonance Imaging (MRI) traditionally requires strong magnetic fields, limiting accessibility.
  • Laser-polarized helium-3 (³He) gas offers a promising alternative for lung imaging due to its sensitivity.
  • Developing open-access, low-field MRI systems is crucial for broader clinical application.

Purpose of the Study:

  • To introduce a prototype system for open-access, very-low-field MRI of human lungs.
  • To demonstrate the feasibility of using laser-polarized ³He gas for lung imaging.
  • To address the technical challenges associated with low-field MRI.

Main Methods:

  • Construction of an open four-coil electromagnet system with a 4 mT operational field.
  • Implementation of planar gradient coils for spatial encoding.
  • Acquisition of ³He and proton (¹H) phantom and human lung images.

Main Results:

  • Successful generation of ³He and ¹H phantom images.
  • Obtained supine and upright ³He lung images in human subjects.
  • Identified and discussed challenges in low-frequency (50-200 kHz) imaging, including noise and coil bandwidth.

Conclusions:

  • The prototype system demonstrates the potential for open-access, very-low-field MRI of the lungs.
  • Laser-polarized ³He MRI is a viable technique for pulmonary imaging.
  • Further development is needed to overcome low-field imaging challenges for clinical translation.