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Related Concept Videos

Mutations01:35

Mutations

Mutations are changes in the sequence of DNA. These changes can occur spontaneously or they can be induced by exposure to environmental factors. Mutations can be characterized in a number of different ways: whether and how they alter the amino acid sequence of the protein, whether they occur over a small or large area of DNA, and whether they occur in somatic cells or germline cells.
Chromosomal Alterations Are Large-Scale Mutations
While point mutations are changes in a single nucleotide in...
Pigmentation01:19

Pigmentation

The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
Role of Skin in Vitamin D Synthesis01:23

Role of Skin in Vitamin D Synthesis

The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin D3(cholecalciferol).
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Photoreceptors and Plant Responses to Light02:00

Photoreceptors and Plant Responses to Light

Light plays a significant role in regulating the growth and development of plants. In addition to providing energy for photosynthesis, light provides other important cues to regulate a range of developmental and physiological responses in plants.

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Studying Chronic Exposure of Mice to Ultraviolet B Radiation
03:20

Studying Chronic Exposure of Mice to Ultraviolet B Radiation

Published on: August 19, 2025

Sunscreens and occupation: the Austrian experience.

Harald Maier1, Alois W Schmalwieser

  • 1Department of Dermatology, Medical University of Vienna, Währinger Gürtel, Vienna 1090, Austria.

Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology
|April 1, 2010
PubMed
Summary

Outdoor workers face significant UV exposure risks, necessitating improved sunscreens. Current products often fail to meet outdoor workers

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Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
12:37

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model

Published on: September 7, 2013

Area of Science:

  • Dermatology
  • Occupational Health
  • Photoprotection Science

Background:

  • Shifting societal attitudes towards tanned skin have increased sun exposure.
  • Ultraviolet (UV) radiation is an underestimated risk factor for skin and eye conditions.
  • Growing discussion on UV-induced skin tumors as occupational diseases highlights this risk.

Purpose of the Study:

  • To emphasize the underappreciated risk of UV radiation for outdoor workers.
  • To explore the factors influencing UV exposure in outdoor work environments.
  • To identify the need for effective photoprotective measures for this population.

Main Methods:

  • Analysis of factors influencing UV exposure: ambient radiation, work processes, and worker behavior.
  • Evaluation of the combined risk from occupational and leisure UV exposure.
  • Assessment of requirements for topical sunscreens suitable for outdoor workers.

Main Results:

  • Outdoor workers experience significant UV exposure influenced by multiple factors.
  • Total risk of actinic damage is a sum of occupational and leisure UV exposure.
  • Few available sunscreens meet the specific criteria (cost, water resistance, feel) for outdoor workers.

Conclusions:

  • There is a critical need for enhanced photoprotective strategies for outdoor workers.
  • Current sunscreen formulations and acceptance by outdoor workers are inadequate.
  • Significant improvements in sunscreen development and user education are required for effective UV protection.