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Related Concept Videos

Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Urinary Tract Infection II: Pathophysiology01:25

Urinary Tract Infection II: Pathophysiology

The pathophysiology of urinary tract infections (UTIs) encompasses several progressive stages, beginning with bacterial colonization and culminating in potential systemic complications if untreated. UTIs are primarily initiated by bacteria, such as Escherichia coli, which often originate from the gastrointestinal tract and migrate to the urinary system through the periurethral area. This migration can occur via several routes, including improper hygiene practices, sexual activity, or...
Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...

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Updated: Jun 14, 2026

Trans-vivo Delayed Type Hypersensitivity Assay for Antigen Specific Regulation
11:49

Trans-vivo Delayed Type Hypersensitivity Assay for Antigen Specific Regulation

Published on: May 2, 2013

Complex bacterial infections pre- and posttransplant.

Erika D Lease1, David W Zaas

  • 1Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA.

Seminars in Respiratory and Critical Care Medicine
|April 1, 2010
PubMed
Summary
This summary is machine-generated.

Lung transplant recipients face serious infection risks, especially those with cystic fibrosis (CF). This review details managing pre- and post-transplant infections from Pseudomonas aeruginosa and other resistant bacteria.

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Last Updated: Jun 14, 2026

Trans-vivo Delayed Type Hypersensitivity Assay for Antigen Specific Regulation
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Bone Marrow Transplantation Platform to Investigate the Role of Dendritic Cells in Graft-versus-Host Disease
08:05

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Published on: March 17, 2020

Area of Science:

  • Medicine
  • Infectious Diseases
  • Transplantation

Background:

  • Infections are a major cause of morbidity and mortality after lung transplantation.
  • Cystic Fibrosis (CF) patients present unique challenges in managing infections post-transplant.
  • Opportunistic infections pose a significant risk to all lung transplant recipients.

Purpose of the Study:

  • To review the clinical impact of specific pre-transplant pathogens in lung transplant recipients.
  • To outline management strategies for infections in lung transplant recipients, particularly those with CF.
  • To discuss the role of Pseudomonas aeruginosa, resistant bacteria, and mycobacteria as both pre- and post-transplant pathogens.

Main Methods:

  • Literature review focusing on infections in lung transplant recipients.
  • Analysis of pre-transplant risk factors and post-transplant pathogen management.
  • Discussion of individual pathogen issues and their impact on outcomes.

Main Results:

  • Pre-transplant infections with Pseudomonas aeruginosa, Stenotrophomonas, Burkholderia, and mycobacteria significantly influence recipient selection and outcomes.
  • Effective management of these pathogens is crucial for improving post-lung transplant survival.
  • Understanding pathogen-specific challenges is key to maximizing the benefits of lung transplantation.

Conclusions:

  • Proactive management of specific bacterial and mycobacterial infections is critical before and after lung transplantation.
  • Tailored strategies are necessary to mitigate infection-related risks in lung transplant recipients, especially those with CF.
  • Addressing these infectious challenges enhances the overall success and long-term benefits of lung transplantation.