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[Percutaneous coronary intervention of patients with complex small coronary artery lesion unsuitable for coronary

Lang Hong1, Hong Wang, Qiu-lin Yin

  • 1Second Department of Cardiology, Jiangxi Provincial People's Hospital, Nanchang 330006, China.

Zhonghua Yi Xue Za Zhi
|April 2, 2010
PubMed

Insights

Percutaneous coronary intervention (PCI) safely and effectively treats complex small coronary artery lesions in patients with low ejection fraction. This procedure improves cardiac function and long-term prognosis for heart failure patients.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Heart Failure Management

Background:

  • Patients with low left ventricular ejection fraction (LVEF) and complex small coronary artery lesions often have limited treatment options.
  • Coronary artery bypass grafting (CABG) may not be suitable for all patients with these complex conditions.

Purpose of the Study:

  • To evaluate the safety and efficacy of percutaneous coronary intervention (PCI) in patients with low LVEF and complex small coronary artery lesions.
  • To assess the impact of PCI on cardiac function, LVEF, and major adverse cardiac events (MACE) over a 12-month follow-up period.

Main Methods:

  • PCI revascularization was performed on 16 patients unsuitable for CABG.
  • Outcomes assessed included immediate procedural success, complications, hospitalization duration, cardiac function, LVEF, and MACE at 12 months.
  • Coronary angiography was used for re-examination at 12 months.

Main Results:

  • All PCI procedures were successful with no deaths or severe complications; hospitalization averaged 11 days.
  • At 12 months, no MACE were reported, cardiac function improved from NYHA class III-IV to I-II, and LVEF increased from 29% to 37%.
  • Left ventricular end-diastolic diameter decreased, and coronary angiography showed no intra-stent thrombosis, with restenosis in 2 cases.

Conclusions:

  • PCI is a safe and effective treatment for patients with low LVEF and complex small coronary artery lesions.
  • PCI can reduce mortality in coronary heart disease patients with heart failure.
  • The procedure improves long-term patient prognosis and cardiac function.
Abstract

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