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Updated: Jun 14, 2026

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
Right mini-thoracotomy for left maze with transesophageal echo guidance
Paolo Vanelli1, Massimo Lemma, Carlo Antona
1Department of Cardiovascular Surgery, Luigi Sacco University General Hospital, Via G.B. Grassi 74, 20157 Milan, Italy. vanelli.paolo@hsacco.it
Minimally invasive surgery using the Epicor low profile system effectively ablated atrial fibrillation (AF) in ten patients. This high-intensity focused ultrasound approach demonstrated safety and efficacy, leading to normal sinus rhythm post-procedure.
Area of Science:
- Cardiology
- Minimally Invasive Surgery
- Medical Devices
Background:
- Atrial fibrillation (AF) ablation is advancing with minimally invasive surgery (MIS) techniques.
- New instrumentation and surgical expertise enable epicardial ablation on beating hearts, reducing risks and improving recovery.
Purpose of the Study:
- To describe the use of the Epicor low profile (LP) system with high-intensity focused ultrasound (HIFU) for AF ablation via MIS.
- To evaluate the safety and efficacy of this novel approach guided by transesophageal echocardiography (TEE).
Main Methods:
- Ten patients underwent monolateral small thoracotomy for epicardial ablation.
- HIFU was used to create an epicardial box lesion around pulmonary veins and the mitral isthmus.
- TEE guided the ablation device positioning on the mitral isthmus.
Main Results:
- No mortalities or major complications, including pacemaker implantation, were observed.
- One patient experienced transient atrial tachycardia, and three had temporary AF requiring cardioversion.
- All patients achieved normal sinus rhythm during the follow-up period.
Conclusions:
- The Epicor LP system using HIFU is a safe and effective option for AF ablation.
- This single right minimally invasive approach offers a promising alternative for AF treatment.
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