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Updated: Jun 14, 2026

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder
Published on: April 26, 2024
Using self-reports of symptom severity to measure and manage workplace depression
Harris Allen1, Zorianna Hyworon, Alberto Colombi
1School of Public Health, Yale School of Medicine, New Haven, Conn, USA. harris-allen@msn.com
Objectives:
To test the workplace impact of depression when it is stratified by severity and considered in broader context.
Methods:
Structural equation models of health risk appraisal data (n = 39,097) involving 41 measures of contextual characteristics, depression severity, health, and job performance.
Results:
Approximately 15.7% exhibited mild depression, whereas 6.9% recorded moderate to severe symptoms. Depression severity exerted large effects on general health and productivity loss, with the mild group posting the largest aggregate impact. Adverse personal life impact and financial concerns more significantly affected moderate to severe depression. In contrast, factors more directly amenable to employer health management efforts (eg, stressful job) better predicted mild depression.
Conclusions:
These results link depression to large health and productivity deficits. They call for public-private collaboration, parity in mental and physical health benefits, and resource allocation that is proportionate across the depression spectrum and facilitated by symptom severity screening.
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