Related Experiment Video
Updated: Jun 14, 2026

Assessing Cytotoxicity of Metabolites of Typical Triazole Pesticides in Plants
Published on: December 22, 2023
Toxic plants: a chemist's perspective
1Department of Chemistry and Biochemistry, Julian Science and Mathematics Center, DePauw University, Greencastle, IN 46135, USA. hanson@depauw.edu
Abstract:
Chemistry has long been an integral part of toxicology, as the two fields originated in much the same way: the investigation of plants with interesting properties. In this chapter I review the role that chemistry has played in understanding toxic and medicinal plants. After some introductory remarks, three broad areas are addressed: the role of natural products in understanding plant taxonomy and evolution, recent developments in chemical synthesis, especially efforts to discover and efficiently synthesize novel structures based upon naturally occurring toxins, and finally, developments in the new field of systems toxicology, which seeks to integrate all aspects of an organism's response to toxic insult.
More Related Videos
11:14Rapid High-throughput Species Identification of Botanical Material Using Direct Analysis in Real Time High Resolution Mass Spectrometry
Published on: October 2, 2016
11:38High Content Screening Analysis to Evaluate the Toxicological Effects of Harmful and Potentially Harmful Constituents (HPHC)
Published on: May 10, 2016
Related Concept Videos
Types of Toxins
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...
Toxic Reactions: Overview
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
Antidotes
Specific antidotes operate by inhibiting the enzymes that control biochemical pathways, reducing the production of harmful metabolites.
An example of an antidote is atropine, which counteracts the detrimental effects of cholinesterase inhibitors. It achieves this by deactivating muscarinic receptors,...
Effects of Chemicals: Overview
Toxicokinetics: Overview
Drug Toxicity: Overview