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Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
Intussusception and colonic ischemia in portal hypertension: a case report
Timothy P Plackett1, Lisa C Coviello, Christina M Belnap
1Department of Surgery, Tripler Army Medical Center, Honolulu, HI, USA.
Insights
Adult intussusception is rare and often requires surgery. This case highlights portal hypertension-induced colopathy as a cause of intussusception and ischemic colitis in adults.
Area of Science:
- Gastroenterology
- Hepatology
- Vascular Surgery
Background:
- Intestinal intussusception is uncommon in adults, typically necessitating surgical resection due to neoplastic lead points.
- Ischemic colitis is a less frequent indication for surgical removal of intussuscepted segments in adults.
- Portal hypertension is associated with microvascular colopathy, potentially leading to intestinal intussusception.
Observation:
- The authors report an unusual case of adult intussusception with ischemic colitis.
- The patient had portal hypertension and was awaiting liver transplantation.
- Portal hypertension-induced microvascular colopathy may have served as the lead point for intussusception.
Findings:
- The colopathy of portal hypertension may predispose adults to intussusception via submucosal vascular engorgement.
- Vascular changes in portal hypertension can impair the bowel's response to ischemic threats.
- The intussuscepted segment in this patient was more susceptible to ischemia due to underlying vascular changes.
Implications:
- This case suggests portal hypertension-induced colopathy as a novel lead point for adult intussusception.
- Understanding these vascular changes is crucial for managing intussusception in patients with portal hypertension.
- Further research may elucidate the specific mechanisms linking portal hypertension, colopathy, and intussusception in adults.
Abstract:
Intestinal intussusception is a relatively uncommon occurrence in adults in comparison to pediatric patients. While the management of intussusception in children is frequently decompression of the involved segment, adults often require surgical resection secondary to frequent association with neoplastic lead points. A less common reason for surgical removal of an intussuscepted segment in adults is the development of ischemic colitis. The authors present an unusual case of adult intussusception with associated ischemic colitis in a patient with portal hypertension awaiting liver transplantation. Portal hypertension is associated with the development of a microvascular colopathy This condition may serve as the lead point for intestinal intussusception. Furthermore, the vascular changes of portal hypertension leave the bowel unable to respond appropriately to the threat of ischemia. The colopathy of portal hypertension may have predisposed our patient to the development of colonic intussusception by submucosal vascular engorgement; it may have also rendered the intussuscepted segment more susceptible to the development of ischemia.
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