Related Experiment Video
Updated: Jun 14, 2026

Signal Acquisition, Score Interpretation, and Economics of a Non-Invasive Point-of-Care Test for Coronary Artery Disease
Published on: August 9, 2024
Identifying the optimal search strategy for coronary heart disease patients in primary care electronic patient record
Krish Thiru1, Peter T Donnan, Peter Weller
1Great Ormond Street Hospital, Cardiac Critical Care Services, Great Ormond Street Hospital, London, UK. Thiruk1@city.ac.uk
Objectives:
General practitioners are increasingly required to practice in a paperless environment and to collect clinical data electronically on electronic patient record (EPR) systems. A principal step in meeting general practice information needs continues to be the establishment of disease registers and consequently the identification of patient populations within primary care databases is a prerequisite. This study aims to identify and validate the optimal search strategy for coronary heart disease (CHD).
Methods:
A multiple logistic regression model for the identification of CHD patients was developed in one site using electronic data, the receiver operating characteristic (ROC) curve and Bayesian statistics. The model was tested on two trial sites.
Results:
Young male CHD patients are more easily identified by generic searches than older females. The optimal search strategy for CHD was found to be the diagnostic code for CHD, nitrate and digoxin but this was dependent on the disease description, age and sex of the study population and the coding system used within the database. Diagnostic code for CHD identified 80.6% (95% confidence interval (CI) 77-83%), 90.0% (CI 88-92%) and 95.9% (CI 94-97%) of local, national and international definitions respectively, with 100% positive predictive values (PPVs) for all definitions.
Conclusion:
Generic queries may inadvertently perpetuate inequalities in health care. Queries should be bespoke and mindful of the conceptualization of disease by the clinicians recording these data.
Related Concept Videos
Coronary Artery Disease V: Interprofessional Care
Coronary Artery Disease IV: Preventive Measures
Acute Coronary Syndrome IV: Interprofessional Care
Assessment of the Cardiovascular System I: Subjective Data
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
Coronary Artery Disease I: Introduction
Acute Coronary Syndrome III: Diagnostic Studies
