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A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
Published on: May 14, 2013
Restenosis after coronary balloon angioplasty
R A Lange1, E D Flores, L D Hillis
1Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas 75235.
Abstract:
A recurrence of stenosis (restenosis) following successful coronary angioplasty continues to be a frequent problem limiting the long-term efficacy of the procedure. An overexuberant reparative response to the arterial injury induced by balloon dilatation leads to intimal hyperplasia, the major mechanism responsible for restenosis. Although none has yet been proven effective, agents designed to prevent this hyperplastic response are under investigation.
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