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Lipoprotein transport gene abnormalities underlying coronary heart disease susceptibility
1Laboratory of Biochemical Genetics and Metabolism, Rockefeller University, New York, New York 10021-6399.
Annual Review of Medicine
|January 1, 1991
Abstract:
There is a close association between lipoprotein abnormalities and coronary heart disease susceptibility. Since 1982, the genes for the lipoprotein transport proteins have been isolated and at least partially characterized. Mutations in these genes are now being defined that underlie the common abnormalities found in heart attack victims. This review presents our current state of knowledge on this subject.