Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Drug Therapy

Drug Therapy

The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications

Psychosis: Goals of Pharmacotherapy

Psychosis: Goals of Pharmacotherapy

Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation. For...

Psychosis and Antipsychotic Drugs: Overview

Psychosis and Antipsychotic Drugs: Overview

The term "psychosis" refers to a spectrum of mental disorders characterized by abnormal thoughts, perceptions, and behaviors. It can manifest as mood disorders, dementia, delirium with psychotic features, substance-induced psychosis with psychotic features, brief psychotic disorder, delusional disorder, schizoaffective disorder, and schizophrenia. Among all these disorders, schizophrenia is the most common psychotic disorder, affecting 1% of the worldwide population. Psychotic symptoms in all...

Positive Symptoms of Schizophrenia: Hallucinations and Delusions

Positive Symptoms of Schizophrenia: Hallucinations and Delusions

Schizophrenia is a complex mental health disorder that can manifest with various positive symptoms, including thought, movement, and behavior disorders. These symptoms significantly disrupt cognitive and motor functions, leading to profound effects on an individual's ability to engage with the world.
Thought Disorders
Disorganized and unusual thought processes mark thought disorders in schizophrenia. One key feature is disorganized speech, where an individual's conversation includes loosely...

Psychological and Sociocultural Causes of Schizophrenia

Psychological and Sociocultural Causes of Schizophrenia

Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...

Negative and Cognitive Symptoms of Schizophrenia

Negative and Cognitive Symptoms of Schizophrenia

Negative symptoms of schizophrenia indicate a reduction or absence of typical behaviors and emotional responses found in healthy individuals, while positive symptoms reflect an excess or distortion of normal functioning.
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Evaluating Safety Concerns for Pediatric Mental and Behavioral Health Patients and Providers in the Emergency Department: A Systems Perspective.

Journal of patient safety·2025

Same author

Using patient journey mapping and provider workflows to understand process barriers to pediatric mental and behavioral health care in emergency departments.

Applied ergonomics·2025

Same author

Technological barriers to providing pediatric mental and behavioral healthcare in emergency departments.

Applied ergonomics·2024

Same author

Adherence, health care utilization, and costs between long-acting injectable and oral antipsychotic medications in South Carolina Medicaid beneficiaries with schizophrenia.

Journal of managed care & specialty pharmacy·2024

Same author

Harbingers of Hope: Scientists and the Pursuit of World Peace.

Clinical psychology in Europe·2024

Same author

Artificial intelligence is set to transform mental health services.

CNS spectrums·2023

Same journal

Unanticipated Effects of Parental Social Media Use: Guidance for Clinicians.

Psychiatric services (Washington, D.C.)·2026

Same journal

Learning About Stigma From Inside the Classroom.

Psychiatric services (Washington, D.C.)·2026

Same journal

Characteristics of Clinical Supervision Associated With Improvements in Youth Outcomes in Community Mental Health Clinics.

Psychiatric services (Washington, D.C.)·2026

Same journal

VA Health Care Utilization Among U.S. Veterans: The Influence of Social Determinants of Health and Health Factors.

Psychiatric services (Washington, D.C.)·2026

Same journal

Defining Digital Peer Support: A Framework to Preserve Core Values in the Rush to Digitize.

Psychiatric services (Washington, D.C.)·2026

Same journal

Perspectives of Individuals With Lived Experience on Obsessive-Compulsive Disorder Treatment Delivery, Supports, and Research.

Psychiatric services (Washington, D.C.)·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 14, 2026

Development of a Virtual Reality Assessment of Everyday Living Skills

Development of a Virtual Reality Assessment of Everyday Living Skills

Published on: April 23, 2014

Simplifying adherence in schizophrenia.

Suzanne M Hardeman¹, Richard K Harding, Meera Narasimhan

¹Department of Neuropsychiatry and Behavioral Science, University of South Carolina School of Medicine, 3555 Harden St., Suite 301, Columbia, SC 29203, USA. shardeman@uscmed.sc.edu

Psychiatric Services (Washington, D.C.)

|April 3, 2010

Summary

This summary is machine-generated.

Improving medication adherence in schizophrenia requires personalized, multidisciplinary strategies. A comprehensive model integrating education, psychotherapy, and therapeutic alliance is presented to enhance patient treatment adherence and outcomes.

More Related Videos

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder

Published on: January 9, 2015

Related Experiment Videos

Last Updated: Jun 14, 2026

Development of a Virtual Reality Assessment of Everyday Living Skills

Development of a Virtual Reality Assessment of Everyday Living Skills

Published on: April 23, 2014

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder

Published on: January 9, 2015

Area of Science:

Psychiatry
Clinical Psychology
Pharmacology

Background:

Treatment nonadherence is a persistent clinical challenge, particularly impacting schizophrenia prognosis.
Medication adherence remains a critical factor influencing patient outcomes in schizophrenia management.

Purpose of the Study:

To present a comprehensive model for improving medication adherence in schizophrenia.
To integrate evidence-based strategies focusing on patient-specific needs.

Main Methods:

The model emphasizes a multidisciplinary approach.
Key components include educational strategies, psychotherapeutic techniques, and fostering a strong therapeutic alliance.

Main Results:

No single strategy is universally effective for all patients.
Customized, multidisciplinary interventions demonstrate improved adherence rates.

Conclusions:

A comprehensive, individualized model is essential for enhancing schizophrenia treatment adherence.
Integrating educational, psychotherapeutic, and alliance-focused strategies can optimize patient care.