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Related Experiment Video

Updated: Jun 14, 2026

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
06:46

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery

Published on: September 27, 2024

Multiple primary malignancies--epidemiological analysis at a single tertiary institution.

Alexandru Irimie1, Patriciu Achimas-Cadariu, Claudia Burz

  • 1Institute of Oncology Prof. Dr. Ion Chiricuta, Cluj-Napoca, Romania.

Journal of Gastrointestinal and Liver Diseases : JGLD
|April 3, 2010
PubMed
Summary

Multiple primary malignancies (MPMs) require consideration during cancer evaluation. Effective screening and patient monitoring are crucial for early detection and management of secondary cancers.

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Area of Science:

  • Oncology
  • Epidemiology
  • Cancer Research

Background:

  • The prevalence of multiple primary malignancies (MPMs) ranges from 0.73% to 11.7% in cancer patients.
  • MPMs appear to occur more frequently than predicted by hazard alone.

Purpose of the Study:

  • To gather clinically relevant data for effective screening of synchronous and metachronous second primary cancers.
  • To propose a potential surveillance protocol for managing MPMs.

Main Methods:

  • Utilized statistical and epidemiological indicators to analyze patients with MPMs.
  • Evaluated 63 patients with double primary malignancies admitted to the Institute of Oncology, Cluj-Napoca, between 2001 and 2004.

Main Results:

  • Identified 22 synchronous (34.9%) and 41 metachronous (65.1%) tumors, with metachronous intervals averaging 34.6 months.

Related Experiment Videos

Last Updated: Jun 14, 2026

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
06:46

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery

Published on: September 27, 2024

  • Observed frequent malignant associations including ovary-colon, ovary-breast, and breast-breast.
  • Noted advanced stages for both primary and secondary tumors, linked to poor patient follow-up compliance.

    • Conclusions:

    • MPMs should be considered during pretreatment evaluation.
    • Screening aids early detection of associated tumors.
    • Regular patient monitoring and strong patient-provider communication are vital for early secondary tumor detection and management.