Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Multiple glomus tumors.

M C Pepper, R Laubenheimer, D J Cripps

    Journal of Cutaneous Pathology
    |October 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Blue Rubber Bleb Nevus Syndrome and Multiple Glomus Tumors can present with similar vascular lesions. Histology reveals distinct differences in glomus cell mantle size and distribution, aiding differentiation.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Verrucous plaques on the face. North American blastomycosis.

    Archives of dermatology·2000
    Same author

    Granulomatous dermatitis with focal sarcoidal features associated with recombinant interferon beta-1b injections.

    Journal of the American Academy of Dermatology·1998
    Same author

    Actinic reticuloid: action spectra and UVA protection factor sunscreens.

    Clinical and experimental dermatology·1992
    Same author

    PUVA and skin cancer. A historical cohort study on 492 patients.

    Journal of the American Academy of Dermatology·1992
    Same author

    Erythematous auricular papules. Angiolymphoid hyperplasia with eosinophilia.

    Archives of dermatology·1990
    Same author

    A preliminary study on the link between PUVA and skin cancer.

    International journal of dermatology·1989

    Area of Science:

    • Vascular Pathology
    • Dermatology
    • Genetics

    Background:

    • Blue Rubber Bleb Nevus Syndrome (BRBNS) and Multiple Glomus Tumors (MGT) are rare vascular disorders.
    • Distinguishing between these conditions is crucial for accurate diagnosis and management.
    • Genetic factors may play a role in the inheritance of these syndromes.

    Observation:

    • A patient with BRBNS-like lesions and his son with MGT were studied.
    • Lesions varied in presentation, with some being painless and others painful with recurrences.
    • Histological examination revealed differences in vascular channels and glomus cell distribution.

    Findings:

    • Asymptomatic tumors showed narrow glomus cell mantles around dilated channels.
    • Painful tumors exhibited larger glomus cell foci with wider mantles around flattened channels.

    Related Experiment Videos

  • Electron microscopy confirmed glomus cells as modified smooth muscle cells.

    • Implications:

    • Histopathology is key to differentiating MGT from BRBNS.
    • MGT may originate from cutaneous vessels rather than Sucquet-Hoyer canals.
    • Understanding the cellular origin of MGT can inform future research and treatment strategies.