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[Massive necrotizing adenitis complicating a disseminated herpes simplex virus 2 infection in chronic lymphoid
C Pierre1, D Jaubert, E Carloz
1Service d'anatomie pathologique, Hôpital d'Instruction des Armées Ste Anne, Toulon Naval.
Annales De Pathologie
|January 1, 1991
Abstract:
We report a case of a 68 years old male patient treated for chronic lymphocytic leukaemia, presenting a right inguino-crural tender lymphadenopathy with periadenitis. The histologic changes associated with adenitis were large foci of necrosis with regular crown of epithelioid cells, without giant cell. The presence of Herpes simplex virus 2 was confirmed by immunohistochemistry and culture. Occurrence, physiopathology, clinical and histological aspects of Herpes simplex lymphadenitis in patients with haematologic disorders, are discussed.