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Related Experiment Video

Updated: Jun 14, 2026

Ferric Chloride-induced Thrombosis Mouse Model on Carotid Artery and Mesentery Vessel

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Published on: June 29, 2015

[Multiple arterial thrombosis in Behçet's disease].

A Kallel¹, M I Miladi, S Marzouk

¹Service de neurologie, hôpital universitaire Habib Bourguiba, CP 3029 Sfax, Tunisie.

La Revue De Medecine Interne

|April 6, 2010

Summary

Behcet's disease can cause rare but severe arterial thrombosis, including in the carotid and pulmonary arteries. Further research is needed to understand its pathogenesis and optimize treatment for this rare vascular complication.

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Area of Science:

Vascular Medicine
Rheumatology
Immunology

Background:

Behcet's disease (BD) is a multisystemic vasculitis with unknown etiopathogeny.
Vascular involvement is common in BD, with venous thrombosis (30%) being most frequent.
Arterial involvement is rare (2.7–7%) but often severe and life-threatening.

Observation:

A 45-year-old Tunisian male presented with Behcet's disease.
The patient exhibited bifocal arterial involvement.
Specific manifestations included right internal carotid artery thrombosis and bilateral proximal pulmonary artery thrombosis.

Findings:

The case highlights a rare instance of extensive arterial thrombosis in Behcet's disease.
The patient presented with simultaneous thrombosis in a major cerebral artery and the pulmonary arteries.
This presentation underscores the potential severity of vascular complications in BD.

Implications:

The pathogenesis of arterial thrombosis in Behcet's disease remains unclear.
Effective therapeutic strategies for managing extensive arterial involvement in BD require further investigation.
This case prompts further research into the mechanisms underlying BD-associated arterial thrombosis and its management.