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Published on: September 19, 2018

Long-term cardiovascular outcome after elective abdominal aortic aneurysm open repair

M Vega de Céniga1, L Estallo, A Barba

  • 1Department of Angiology and Vascular Surgery, Hospital de Galdakao-Usansolo, Galdakao-Usansolo, Bizkaia, Spain. melina.vegadeceniga@osakidetza.net

Annals of Vascular Surgery
|April 6, 2010
PubMed

Insights

Patients undergoing open repair for abdominal aortic aneurysms face a lifelong risk of cardiovascular events, despite good long-term survival. Graft complications are infrequent, highlighting the procedure's durability.

Area of Science:

  • Vascular Surgery
  • Cardiovascular Medicine
  • Epidemiology

Background:

  • Assessing long-term outcomes after open repair of infra-/juxtarenal abdominal aortic aneurysms (AAA-OR).
  • Evaluating the incidence of late cardiovascular events and mortality in patients who underwent AAA-OR.

Purpose of the Study:

  • To analyze the long-term incidence of cardiovascular events and mortality post-elective infra-/juxtarenal abdominal aortic aneurysm open repair (AAA-OR).
  • To identify risk factors associated with cardiovascular mortality in this patient cohort.

Main Methods:

  • Inclusion of patients who survived AAA-OR between 1988-2006.
  • Registration of late cardiac, cerebrovascular, and peripheral vascular events, alongside all-cause and cardiovascular mortality.
  • Calculation of patient survival and freedom from cardiovascular events using Kaplan-Meier analysis and evaluation of risk factors via multivariate analysis.

Main Results:

  • A total of 297 patients (98.3% male, mean age 67 years) were studied with a mean follow-up of 78.7 months.
  • 203 cardiovascular events occurred in 123 patients (41.4%), with cardiovascular disease being the primary cause of death (18.2%).
  • Long-term freedom from cardiovascular events was 27.6% at 15 years; survival was 31.5% at 15 years. Coronary artery disease and chronic renal failure predicted cardiovascular mortality.

Conclusions:

  • Successful AAA-OR patients face a persistent, elevated risk of cardiovascular events throughout their lives.
  • Long-term survival after AAA-OR is comparable to the general population.
  • Graft-related complications are rare, underscoring the durability of open repair for abdominal aortic aneurysms.
Abstract

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