Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Extracorporeal Removal of Drugs: Hemoperfusion and Hemofiltration01:25

Extracorporeal Removal of Drugs: Hemoperfusion and Hemofiltration

Hemoperfusion and hemofiltration are critical techniques in medical treatments to eliminate accumulated drugs, metabolites, and electrolytes from the bloodstream. These methods are particularly vital in cases of accidental poisoning and drug overdose.Hemoperfusion involves passing blood through an adsorbent material to remove unwanted substances. The main adsorbents used in hemoperfusion include activated charcoal and Amberlite resins. Activated charcoal can adsorb both polar and nonpolar...
Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy01:26

Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy

Continuous Renal Replacement Therapy (CRRT) is an essential intervention for patients experiencing severe kidney dysfunction. This therapy offers a continuous mechanism for removing fluids and toxins from the bloodstream, leveraging the patient’s blood pressure to facilitate filtration through a specialized filter. This method contrasts with intermittent dialysis, providing a gentler and more consistent removal of waste products and excess fluid, which is particularly beneficial in critically...
Blood Transfusion01:15

Blood Transfusion

Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Blood Transfusion and Agglutination02:45

Blood Transfusion and Agglutination

Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
Heart Failure VI: Adjunct Therapies01:22

Heart Failure VI: Adjunct Therapies

Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.
Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure01:16

Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure

Oxygen therapy has emerged as a significant tool in enhancing the quality of life for patients suffering from pulmonary arterial hypertension (PAH). While this therapy has principally been studied on patients with significant hypoxemia, this therapeutic approach helps prevent potential organ damage and can be administered in the comfort of one's home.
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue, improving...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

DNA methylation inhibitor decitabine ameliorates spondyloarthritis by suppressing Th17 responses and epigenetically upregulating VIPR1 in SKG mice.

Arthritis research & therapy·2026
Same author

Tocilizumab as a Potential Alternative Therapy for Acute Exacerbation of Systemic Sclerosis-Associated Interstitial Lung Disease in a Dialysis Patient Following Immunodeficiency-Associated Lymphoproliferative Disorders.

Cureus·2026
Same author

Three-drug combination therapy to prevent glucocorticoid-associated osteonecrosis in patients with systemic lupus erythematosus: a proof-of-concept study.

Therapeutic advances in musculoskeletal disease·2026
Same author

Prophylactic Effect of Trimethoprim-sulfamethoxazole on Severe Infections in Idiopathic Inflammatory Myopathy.

Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases·2026
Same author

Effectiveness and safety of rituximab for remission maintenance therapy in microscopic polyangiitis and granulomatosis with polyangiitis in Japan: A retrospective multicenter cohort study (J-CANVAS).

Modern rheumatology·2026
Same author

Clinical characteristics of giant cell arteritis with ocular involvement: A single-centre retrospective study.

Modern rheumatology·2026

Related Experiment Video

Updated: Jun 14, 2026

Automated Counterflow Centrifugal System for Small-Scale Cell Processing
04:49

Automated Counterflow Centrifugal System for Small-Scale Cell Processing

Published on: December 12, 2019

Current topics on therapeutic apheresis.

Ken Yamaji1

  • 1Department of Internal Medicine and Rheumatology, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo, 113-8421, Japan. k.yamaji@juntendo.ac.jp

Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs
|April 6, 2010
PubMed
Summary

Therapeutic apheresis offers a safer, more effective complement to pharmacotherapy, mitigating tissue injury from treatments like immunosuppressants. This approach is being explored for various conditions, enhancing drug therapy outcomes.

Related Experiment Videos

Last Updated: Jun 14, 2026

Automated Counterflow Centrifugal System for Small-Scale Cell Processing
04:49

Automated Counterflow Centrifugal System for Small-Scale Cell Processing

Published on: December 12, 2019

Area of Science:

  • Pharmacotherapy and Immunomodulation
  • Medical Technology and Apheresis

Background:

  • Recent advances in pharmacotherapy (immunosuppressants, biologics) show promise but face limitations.
  • Challenges include drug resistance, organ damage, allergies, and adverse drug reactions, hindering treatment efficacy.
  • Therapeutic apheresis is emerging as a strategy to enhance pharmacotherapy safety and effectiveness.

Purpose of the Study:

  • To discuss new findings on therapeutic apheresis in conjunction with pharmacotherapy.
  • To review current insurance-covered applications for rheumatoid arthritis, ulcerative colitis, and chronic hepatitis C.
  • To explore potential future coverage for conditions like dilatative cardiomyopathy, pyoderma gangrenosum, and pulmonary fibrosis.

Main Methods:

  • Review of clinical efficacy and indications for therapeutic apheresis.
  • Analysis of concomitant use of apheresis to mitigate drug-induced tissue injury.
  • Evaluation of current and investigational applications across various autoimmune and inflammatory diseases.

Main Results:

  • Therapeutic apheresis demonstrates potential in managing conditions like rheumatoid arthritis, ulcerative colitis, and chronic hepatitis C.
  • Emerging evidence suggests efficacy for dilatative cardiomyopathy, pyoderma gangrenosum, and pulmonary fibrosis.
  • Apheresis can mitigate severe tissue injury associated with certain pharmacotherapies.

Conclusions:

  • Concomitant therapeutic apheresis presents a viable strategy to improve pharmacotherapy outcomes and patient safety.
  • Expanded insurance coverage for apheresis is warranted for a broader range of debilitating conditions.
  • Further research into apheresis applications will likely enhance treatment paradigms for complex diseases.