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Updated: Jun 14, 2026

Measuring the Carotid to Femoral Pulse Wave Velocity (Cf-PWV) to Evaluate Arterial Stiffness
Published on: May 3, 2018
[Arterial stiffness as a predictor of cardiovascular events in coronary heart disease]
Insights
Arterial stiffness significantly impacts prognosis in chronic diseases. Its role after coronary heart disease (CHD) manifestations requires further investigation for cardiovascular event (CVE) understanding.
Area of Science:
- Cardiovascular Medicine
- Nephrology
- Endocrinology
Context:
- Impaired arterial elasticity is linked to poor outcomes in chronic renal failure, hypertension, and diabetes.
- Coronary heart disease (CHD) accounts for a significant proportion of cardiovascular events (CVEs).
Purpose:
- To review the pathogenetic and clinical aspects of arterial stiffness in relation to cardiovascular events (CVEs).
- To clarify the role and mechanisms of arterial stiffness following coronary heart disease (CHD) manifestations.
Summary:
- Arterial stiffness is a known prognostic factor in chronic kidney disease, hypertension, and diabetes.
- The precise impact and mechanisms of arterial stiffness after coronary heart disease (CHD) events remain incompletely understood.
- Large vessel rigidity may indicate coronary artery disease and exacerbate myocardial ischemia.
Impact:
- Understanding arterial stiffness is crucial for improving cardiovascular event (CVE) prediction and management in high-risk populations.
- This review highlights the need for further research into the specific role of arterial stiffness post-CHD.
- Clarifying these associations can inform therapeutic strategies to mitigate CVE risk.
Abstract:
To date, there is much evidence confirming that impaired arterial elastic properties have a direct impact on prognosis in patients with chronic renal failure, arterial hypertension, or diabetes mellitus in the general population and in the elderly. At the same time, in most cohort studies the manifestations of coronary heart disease (CHD) constitute about two thirds of developed cardiovascular events (CVE); the value of arterial stiffness after CHD manifestations has not been conclusively ascertained. There are various opinions on the mechanism and pattern of this association. Rigidity of large vessels may be a marker of cardiac artery lesion, on the one hand, and promote deterioration of myocardial ischemia in the presence of coronary atherosclerosis, on the other. This review of literature discusses the pathogenetic and clinical aspects of the impact of stiffness of the great vessels on the development of CVE.
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