Tolerance to the foetal allograft?

Gérard Chaouat1, Marie Petitbarat, Sylvie Dubanchet

  • 1U 782 INSERM, Université Paris Sud, and Hôpital Antoine Béclère, Clamart, France. gerard_chaouat@wanadoo.fr

In this review, we will detail the concept of tolerance and its history in reproductive immunology. We will then consider whether it applies to the foetal-maternal relationship and discuss the mechanisms involved in non-rejection of the foeto-placental unit.