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Published on: February 19, 2021
Quantitative evaluation of a clinical intervention aimed at changing prescriber behaviour in response to new
Sophie Doyon1, Mélissa Perreault, Christopher Marquis
1Department of Pharmacy and Research Unit of Pharmacy Practice, CHU Sainte-Justine, Montreal, QC, Canada.
Insights
Disseminating acute community-acquired pneumonia guidelines significantly improved prescriber compliance by over 30% in a pediatric hospital. This led to more appropriate antibiotic selection, enhancing patient care.
Area of Science:
- Pediatric Medicine
- Infectious Diseases
- Healthcare Quality Improvement
Background:
- Acute community-acquired pneumonia (CAP) requires adherence to evidence-based guidelines for optimal management.
- Prescriber compliance with CAP management guidelines can vary significantly in clinical practice.
- Assessing and improving guideline adherence is crucial for enhancing pediatric patient outcomes.
Purpose of the Study:
- To evaluate the impact of disseminating new CAP management guidelines on prescriber compliance.
- To compare prescriber adherence rates before and after guideline implementation in a pediatric hospital.
- To identify specific areas of non-compliance, such as antibiotic selection, and assess improvements.
Main Methods:
- A quasi-experimental study design was employed in a tertiary care pediatric hospital.
- Prescriber compliance was assessed using a compliance score before and after guideline dissemination.
- The intervention involved peer leader consultation, networking, guideline distribution, and educational sessions.
Main Results:
- Prescriber compliance with CAP guidelines increased from 20.1% pre-intervention to 52.9% post-intervention, a 32.8% improvement.
- Inappropriate antibiotic selection, a major cause of non-compliance, decreased from 66.6% to 42.1%.
- Improved compliance was observed in both the emergency department and hospital wards.
Conclusions:
- Guideline dissemination for CAP management significantly enhanced prescriber compliance.
- The intervention effectively improved antibiotic prescribing practices for pediatric CAP.
- These findings support the implementation of guideline dissemination strategies to improve clinical care quality.
Rational, Aims And Objectives:
The objective of the study was to assess prescribers' compliance with guidelines for acute community-acquired pneumonia management in a paediatric university hospital centre before and after its dissemination.
Method:
This quasi-experimental study without a control group was conducted before and after new community-acquired pneumonia management guidelines were disseminated in a tertiary care paediatric hospital. The pre-intervention (baseline) period was from October 2004 to March 2005. The intervention period was divided into two phases: (1) October 2005 to January 14, 2006 (consultation by peer leaders and networking) and (2) January 15, 2006, to March 2006 (dissemination of official guidelines and of a pre-printed prescription sheet, an educational session led by a peer leader for residents and further networking). We used a compliance score to assess prescriptions written by prescribers who practised in the units where the guidelines had to be followed.
Results:
The study included a total of 1151 prescriptions. The prescription compliance with the guidelines increased from 131/652 (20.1%) in the pre-intervention period to 264/499 (52.9%) in the post-intervention intervention period: a difference of 32.8% (CI 95% 27.4-38.0). Similar results were found if analysed according to affiliation (emergency department or wards). An inappropriate choice of antibiotic agent represented 347/521 (66.6%) of the causes of non-compliance in the pre-intervention period and 99/235 (42.1) in the intervention period: a difference of -24.5% (95% CI -31.8, -16.8).
Conclusion:
Guideline dissemination for the management of acute community-acquired pneumonia significantly increased prescriber compliance in the emergency department and on wards.
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