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Related Experiment Video

Updated: Jun 14, 2026

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder

Published on: April 26, 2024

[Time perception in depressed and manic patients].

Qi-yuan Zhao¹, Yi-fu Ji, Kai Wang

¹Department of Neuropsychology, First Affiliated Hospital of Anhui Medical University, Hefei 230022, China.

Zhonghua Yi Xue Za Zhi

|April 7, 2010

Summary

Patients with affective disorders, including depression and mania, exhibit altered time perception. Depressive patients overestimate time, while manic patients underestimate it, suggesting emotion

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Area of Science:

Neuroscience
Psychiatry
Chronopsychology

Context:

Affective disorders, such as depression and mania, significantly impact cognitive functions.
Time perception is a complex cognitive process that can be influenced by emotional states.

Purpose:

To investigate alterations in time perception in patients with affective disorders.
To explore the neurobiochemical mechanisms underlying these temporal distortions.

Summary:

A time reproduction task revealed significant differences in time perception between depressive patients, manic patients, and healthy controls.
Depressive patients consistently overestimated time intervals, whereas manic patients underestimated them.
These temporal perception changes correlated with illness severity, specifically with scores on the Hamilton Depression Rating Scale (HAMD) and the Brief Psychiatric Rating Scale (BRMS).

Impact:

This study highlights the profound effect of emotional states on time perception.
Findings suggest that neurotransmitter systems in the brain play a crucial role in the neurobiological underpinnings of time perception.
Understanding these alterations can inform therapeutic strategies for affective disorders.