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Updated: Jun 14, 2026

Murine Intrapulmonary Tracheal Transplantation: A Model for Investigating Obliterative Airway Disease After Lung Transplantation
Published on: November 10, 2023
A breath of fresh air for lung transplant recipients
1Center for Immunobiology, Departments of Medicine, Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN 46202, USA. dwilkes@iupui.edu
Abstract:
Lung transplantation is a definitive therapy for the treatment of many end-stage lung diseases. However, because of donor-related morbidities, only 15% of donor lungs are suitable for transplantation, which leads to an increased risk of death for prospective patients waiting for this lifesaving procedure. A technique reported by Keshavjee's group in this issue of Science Translational Medicine may help address this problem, not only by repairing donor lungs before transplant, but also by possibly preventing lung injury after transplantation.
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