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Expression and function of matrix Gla protein in human peritoneal mesothelial cells

Yihui Zhai1, Ling Chen, Meike Hömme

  • 11Division of Pediatric Nephrology, Center for Children and Adolescent Medicine, University Hospital for Pediatric and Adolescent Medicine, Heidelberg, Germany.

Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association
|April 7, 2010
PubMed
Summary

Matrix Gla protein (MGP) is expressed by peritoneal mesothelial cells and regulates peritoneal calcification. Suppressing MGP significantly increases calcium and phosphorus deposition, highlighting its role in peritoneal calcium homeostasis.

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