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Updated: Jun 14, 2026

Grade III Varicocele Surgical Treatment using Spermatic Vein-Superficial Abdominal Vein Shunt
Published on: August 23, 2024
[Varicocele and male infertility]
1Department of Andrology, Nanjing General Hospital of Nanjing Military Region, Nanjing, Jiangsu 210002, China. huangyf@androl.cn
Abstract:
Varicocele is a most common and surgically correctable cause of male infertility, for which varicocelectomy is the major treatment. Recent years have witnessed a lot of efforts devoted to the pathomechanism of varicocele-induced male infertility and rapid progress in researches on its cellular and molecular mechanisms, mainly including apoptotic abnormality and oxidative stress of germ cells. Meanwhile, researchers are coming to a consensus on the indications of varicocelectomy as well as the advantages and disadvantage of different methods of the procedure. This review updates the cellular and molecular mechanisms of varicocele-induced male infertility and its clinical therapeutic strategies.
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