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Updated: Jun 14, 2026

Genotyping Single Nucleotide Polymorphisms in the Mitochondrial Genome by Pyrosequencing
Published on: February 10, 2023
Interactions of neanderthals and modern humans: what can be inferred from mitochondrial DNA?
Krzysztof A Cyran1, Marek Kimmel
1Institute of Informatics, Silesian University of Technology, Akademicka 16, 44-100 Gliwice, Poland. chrisc1@rice.edu.
Abstract:
This paper reviews the state-of-the-art knowledge concerning the relationship between Neanderthals and Upper Paleolithic modern humans. The branching-process method is applied to infer the upper limit of hypothetical Neanderthal admixture, consistent with the evidence based on mitochon- drial DNA sequences of contemporary modern humans, as well as Neanderthal and early modern European H. sapiens fossils. As a result, a maximum value of 15% admixture is obtained. This estimate is discussed in the context of its consequences for the two competing theories of modern human origin.
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